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Studies of new drugs traditionally involve at least two groups of people. The people in one of those groups are given only what they think is the drug. Really they get a placebo — an inactive substance. The drug is proven effective if it performs better than the placebo.

Some researchers do not think drug studies should use placebos. They say it makes more sense to compare new medicines to drugs already on the market. Then people would know if a new drug is any better.

“Placebo” is Latin for “I shall please.” It may contain nothing more than sugar.… Read the rest